The Nnamdi Azikiwe University Teaching Hospital, Nnewi was established by Anambra State of Nigeria (ASN) Edict No 10 of 1988 as Anambra State University of Technology Teaching Hospital Nnewi, and shared premises with the then General Hospital, Nnewi.
The General Hospital was officially handed over to the Teaching Hospital Management Board on the 16th June, 1990. Following the handover, a number of essential hospital equipments were either refurbished or renovated.
The Hospital was officially commissioned on Friday 19th July, 1991 by the then Anambra State Military Governor; Col.Robert Akonobi and the General Hospital were taken over as a temporary site. The Federal Government of Nigeria through Decree No 68 of 1992 then renamed the Hospital of Nnamdi Azikiwe University Teaching Hospital in honor of the late saga and foremost politician, Rt. Hon. Dr. Nnamdi Azikiwe GGFR.PC Owelle of Onitsha.
In order to meet the demands of the National Policy on Medical Education which stipulates that batch Teaching Hospital shall be associated with a community Medicare Centre for Community and Primary Healthcare, Neni, Aniocha L.G.A was designated an annex of Teaching Hospital in October,1989 and commissioned on the 27th December,1991.
Another Annex of the Teaching Hospital, the Guinness Eye Hospital Onitsha, Onitsha North L.G.A was handed over to the NAUTH Management Board on the 26th June, 1991, for treatment of eye disorders.
Other annexes of the hospital which were later handed over to her include:
The Centre of Community/Primary Health Care. Ukpo, Dunukofia L.G.A, which was commissioned on the 10th April, 1997.
The Trauma centre Oba, Idemili South L.G.A ceded by the Federal Ministry of Health and commenced services to the community on 28th February, 2005.
Federal Staff Clinic (NAUTH Annex) Awka, Awka South Local Government of Anambra State, which was established in 1999 as Federal Staff clinic to serve the Staff of Federal establishment and their families. It was ceded to NAUTH in May 2008 following the establishment of National Health Insurance Scheme.
The centre of community/primary Health care, Umunya, oyi L.G.A which was commissioned on 17th June, 2005.
Presently, the location of the main Hospital at Nnewi is temporary and it is hoped that in a very near future, the Hospital will move over to its permanent site of over 54hectares landmass at the confluence of Nnewi, Oraifite and Ozubulu towns which is currently being developed.